Novalac AC Vs Similac Total Comfort (A Complete Buying Guide 2023)

Are you trying to choose between Novalac AC Vs Similac Total Comfort? 

The research on each product in this article gives exposure to what you and your baby stand to gain from using any of the brands in terms of its history, ingredients, pros, and cons.

And a concluding verdict on which would be the most suitable for you.

Table of Contents

Novalac AC Vs Similac Total Comfort

Breastfeeding is the natural and best way of nourishing babies in their first weeks of birth.

Breast milk is nutritionally complete and provides sufficient nutrients babies require, and all parents are encouraged to breastfeed their babies if possible.

Unfortunately, not every parent is capable or interested in breastfeeding even though the babies need these nutrients for survival.

Thankfully, certain formulas like the Novalac ac Vs. Similac Total Comfort is designed to provide babies with these nutrients as stand-alone milk formulas or supplements.

Even though both formulas are nutritionally packed and designed to provide the necessary nutrition, they may not fit every baby since all babies are unique.

And as a parent, you may wonder which of the two formulas is more suitable for your baby.

A quick look at each formula will provide you with the insight you need to help with your choice of the perfect milk formula for your infant:

Novalac ac

Novalac AC is an infant milk formula designed for babies with colic.

Colic is a physiological deficiency of lactase, the enzyme responsible for the breakdown of lactose in the small intestine. It is characterized by gas, bloating, flatulence, and constipation.

Inconsolable crying in babies is a sign of colic and can cause much discomfort.

Novalac works by increasing the metabolic processes in the small intestine and promoting the absorption of nutrients to reduce the lactose content in the gut.

It is the first formula developed to help babies with acid reflux, gas, constipation, and other gastrointestinal problems.

During the first weeks of their lives, babies have very sensitive tummies trying to adapt to the world outside the womb.

Their delicate system is not strong enough to digest some nutrients, which leads to much discomfort and cramping in babies.


In 1991, after observing the reactions of some babies to certain formulas, a group of pharmacists, pediatricians, and scientists sought a better way to help babies with gastrointestinal problems.

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They came up with a dietary solution in the form of Novalac milk formula to manage these problems.

Novalac developed the first infant formula for babies with acid reflux, colic, gas, and other related issues.

They are very strict with their manufacturing processes to ensure healthy feeding for babies worldwide.

Some of their strictly monitored processes include:

  • Each delivery of fresh milk is tested before unloading.
  • Every batch of ingredients is sampled and tested before it is used.
  • Raw milk is pasteurized to eliminate all potential pathogens. Pasteurization is the process of heating milk to kill all disease-causing bacteria. After pasteurization, it is filtered to remove any foreign particles.
  • Each ingredient is weighed before adding to the formula to maintain a standard composition.

Novalac is a Latin word for ” New milk,” Just like the name, the emergence of Novalac ac gave a new meaning to babies who suffered from colic and other forms of discomfort associated with formula feeding.


● It is iron-fortified

● Great source of omega 3

● Made for infants from 0 to 12 months


  • Maltodextrins
  • Vegetable Oils (Palm fruit, soy, coconut, tocopherol extract)
  • Skimmed milk
  • Lactose (milk)
  • Milk proteins
  • Minerals (Calcium Chloride, Dipotassium phosphate, magnesium oxide, manganese sulfate, sodium selenite, zinc sulfate, potassium hydroxide, iron sulfate, Copper sulfate, potassium iodide)
  • Vitamins ( A, D3, E, K1, B1, B2, B6, B12, C
  • Niacin
  • Biotin
  • Folic acid
  • Pantothenic acid
  • Emulsifier (soy lecithin, taurine, inositol, L-carnitine
  • Choline Bitartrate


  • It contains probiotics
  • It contains prebiotics
  • It is sucrose free
  • It promotes cognitive development
  • It is a great source of omega-3


  • It increases bowel movement
  • Some parents noticed nauseousness in their infants
  • Thirst
  • Overactivity
  • Altered sleep patterns in some infants

Similac Total Comfort

Similac Total Comfort is a gentle and easy-to-digest formula suitable for babies with difficulty tolerating other milk-based formulas. 

It is a special blend of DHA, Lutein, Vitamin E, and other essential nutrients in breast milk.


Even if you’re new to parenting, you must have come across the name Similac at some point.

Although hearing names of different formula brands may be common, Similac has been around for a while and can be dated to as far back as the 1920s, enough time to earn their popularity.

After it was first released in the 1920s and reformulated and concentrated in 1951.

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It has since consistently provided babies with nourishing formulas that are gentle on their tummies and promote their growth.

And is now sold in about 92 countries around the world.


● Gentle and easy-to-digest for delicate tummies

● Contains nucleotides for the immune system

● It is a Non-GMO formula

● It can help to prevent gas and constipation in babies.

● It has human milk oligosaccharides for the immune system.


  • Corn maltodextrins
  • Whey protein hydrolysate
  • High Oleic safflower oil
  • Sugar
  • Soy oil
  • Coconut oil
  • Less than 2% of C. cohnii oil
  • M. Alpina oil
  • Fructooligosaccharides
  • Beta Carotene
  • Lutein
  • Calcium Citrate
  • Potassium phosphate
  • Calcium phosphate
  • Potassium hydroxide
  • Salt
  • Magnesium chloride
  • Biotin
  • Choline Bitartrate 


  • It promotes healthy bowel movements.
  • Reduces constipation
  • No artificial growth hormones
  • Non-GMO
  • Contains prebiotics


  • Unpleasant smell
  • It might be costly for some families.
  • It foams when you mix it
  • It is not suitable for babies with galactosemia.

Novalac AC Vs Similac Total Comfort


● Both products are gentle and easy-to-digest

● They’re designed to nourish babies from birth up to 12 months

● They both help to reduce gas and constipation in babies

● Both products are nutritionally complete


Novalac ac is the first formula strictly developed for babies with colic. Similac also reduces fussiness, but there’s no guarantee of reducing discomfort in babies from milk-based formulas.

Our Verdict

Always remember to get the recommendation of your baby’s doctor before choosing any formula brand, especially if your baby has any allergies or suffers from other gastrointestinal issues.

Health practitioners are in the best position to suggest what feeding plan your baby needs.

However, suppose you’re familiar with certain brands and are only looking for better brands that reduce fussiness. 

Any product between Novalac AC Vs Similac Total Comfort is ideal for babies with acid reflux and other related tummy issues. Your choice of brand should always seek to meet your baby’s needs.

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Choosing which one is best between Novalac AC Vs Similac Total Comfort is dicey, considering that both share a common denominator of reducing gas, bloating, and constipation while promoting the baby’s growth.

Depending on your baby’s needs and affordability, always seek a doctor’s recommendation to be safe.